Alexander Kuhl
Management Consultant
Experience
Managing Director and Lead Consultant
Prometheus-Innovent Ltd.
- Consulting in the area of Project Management and Product Development
- Intercultural & Organizational Change Management
- Due Diligence Services with focus on strategic insights
- Establishing Problem-Solution-Fit for digital omnichannel marketing strategies incorporating product information management processes, including third party vendor service assessment to enter into RfQ
- Led a change management initiative to establish digital content delivery management readiness, improving technical documentation processes, customer experience and realizing significant cost savings by transitioning from printed to digital content delivery.
Director Engineering Project Management
Fresenius Medical Care R&D Co. Ltd.
- Managed a portfolio of development, technology screening and maintenance projects for the global Business Unit Care Enablement through a stage gate process
- Ensured portfolio performance through project prioritization by resource allocation and budget planning, adhering to financial targets for the solution and container disposables product engineering center (96 projects in 2021)
- Led a multinational team of project managers in North America, Europe and Asia; improved team engagement score by 32% over two years
- Ensured project performance by identifying and communicating project risks and proactively managing risk response strategies, e.g. nitrosamine issue resolution
- Monitored project progress through issue resolution from incubation to commercialization; launched 6L Biofine APD solution bag in North America in 2021
- Served as project management training champion and agile coach for the China design center
- Established an integrated resource allocation and budgeting process based on Planview Enterprise One
- Built a cloud-based project and portfolio management capability for systemized reporting with contextual workflow management
- Implemented an agile project management framework using Scrum-ban during the COVID crisis in Europe and China
- Implemented a stage gated innovation process within the product engineering center, e.g. development of an in-vitro diagnostic device for peritonitis approved by CFDA in October 2022
- Rescoped 6L Biofine Automated Peritoneal Dialysis consumable project, allowing for 20% capacity extension.
Independent Consulter
Independent Consulter
- Consulting & project management in pharmaceuticals, medical devices, diagnostics and consumer goods
- Project & portfolio valuation including business case development
- Intercultural & organizational change management
- Intellectual property generation
- Life science consulting for the General Consulate of Germany in Shanghai
- Led a team of QIAGEN executives to establish a cross-functional strategic assessment and actionable change management plan to restructure QIAGEN China and achieve 200 million USD sales target by 2021
- Established change management plan for the introduction of an enterprise portfolio management system for QIAGEN globally
- Conducted opportunity analysis and project valuation with Shenzhen Hepalink Pharmaceuticals Group for project incubation and product commercialization, including the largest biotech investment in China 2017 of 60 million CAD.
Sr. Director – Head of Portfolio & Project Management, Global Product Development
Pfizer (China) R&D Co. Ltd.
- Established a cross-functional portfolio and project management department across business units, empowering asset teams through project governance principles (9 FTE, 38 assets, 69 projects)
- Led project management activities for all Development China projects from pre-buyup through government approvals, lifecycle management and post-approval commitment plans
- Directed local portfolio prioritization process, ensuring commercial valuations, development plans, costs and success probabilities for buyup decisions
- Acted as single point of contact for project management responsibilities and portfolio valuations to local and global business units
- Supervised, coached and mentored project managers, ensuring skills and capabilities for program delivery
- Ensured development work followed appropriate processes and promoted issue sharing and resolution among teams and governance bodies
- Managed local governance bodies for timely decision making to progress the China portfolio
- Hired, trained and motivated seven project managers and one assistant to implement governance principles
- Established a fully operating portfolio and project management department within three months
- Safeguarded marketing authorizations of Aromasin, Benefix, Xyntha and Vfend through timely escalation and issue resolution
- Aligned China PAC program for Eliquis VTET.
Business Development Manager a.i. – Business Development Asia and Emerging Markets
Roche Ltd. China
- Identified and evaluated partnering opportunities by scientific and commercial profiling of projects and product landscapes
- Prepared scientific and business rationales for in- and out-license opportunities for internal decision makers
- Established target product profiles and product positioning for in-license projects
- Managed partner relationships with proactive communication and follow-up at events such as ChinaBio conference.
Line Manager Clinical Operations I2O, NS & Met – Global Product Development
Roche Ltd. China
- Led a group of global studies leaders, managers and associates with line management and budget responsibility
- Managed staff performance through ongoing performance dialogues and development discussions
- Served as therapeutic program point person to ensure resource efficiencies and delivery of 11 studies in immunology, infectious diseases and neuroscience & metabolics
- Progressed study conduct by proactively addressing resource and study issues with operational program leads, e.g. Pegasys NV25718 LPI delivered six months ahead of schedule
- Consolidated staff training needs and implemented leadership training and coaching programs
- Reduced staff turnover and grew organization by approximately 20% through an inspiring work environment.
Director – Head of Clinical Project Management Development East Asia & Network
UCB Pharma Ltd. China
- Established a regionally cooperating clinical project management organization by transforming CRO operations
- Structured work processes by defining job descriptions and implementing best practices for study management
- Defined and implemented leadership, communication and proficiency competencies
- Supervised and evaluated work performance, establishing workforce planning based on resource modeling
- Recruited, trained and motivated staff, growing China organization by 80% while maintaining headcount
- Improved clinical study management through introduction of KPIs
- Managed 52 studies in CNS and RA (35 million € external cost; 38 FTEs including 4 direct reports).
Director – Global Project Management
Bayer HealthCare Co. Ltd.
- Headed global project and supervised clinical study teams
- Developed products and brands by directing global development projects
- Directed clinical development studies in Phase I, IIb and III
- Managed an overall development budget of 45 million €
- Established global KOL network for hypertension program
- Trained and mentored a team of project managers
- Created Asia-specific diabetes development projects.
Project Leader – Global Project Management
Bayer HealthCare AG
- Led and co-chaired cross-functional global project and brand teams in cardiovascular area (e.g. Adalat, Aspirin, Glucobay)
- Implemented brand and lifecycle management strategies, evaluating 350 potential Aspirin projects to identify and prioritize opportunities
- Led late-stage cardiovascular development projects and cooperated with Boehringer Ingelheim on Phase IIIb studies TALENT and ON TARGET issue management
- Coordinated in- and out-license projects including due diligence and term-sheet negotiations
- Applied fixed dose combination and innovative formulation strategies for marketed products, e.g. Adalat FDC Candesartan
- Managed brand defense projects, delaying generic competitor entry in Canada 2009, preventing over 50 million € sales erosion.
Project Leader – Regulatory Affairs
Bayer Vital GmbH
- Managed regulatory lifecycle activities of ethical and biological products such as Adalat and Gamunex
- Developed regulatory strategies and aligned successfully with health authorities, e.g. re-launch of Aspirin i.v. in Germany
- Achieved 15 NDAs focusing on multinational and European registration procedures for biological products.
Assistant Project Leader – Cardiovascular Research
Bayer HealthCare AG
- Responsible for lead optimization of HTS structures to candidate molecules
- Led optimization of Kerendia (Finerone, Bay 94-8862), a selective non-steroidal mineralocorticoid receptor antagonist for CHF treatment.
Project Coordinator & Laboratory Head – Medicinal Chemistry
Bayer HealthCare AG
- Coordinated lead optimization activities across three laboratory units within strategic medicinal chemistry projects.
Research Fellow
University of Glasgow
- Developed a reagent and applied it in synthesis of natural products
- Conducted research and teaching activities.
Summary
Senior Management Consultant and Founder of Prometheus Innovent Ltd. with 25 years guiding pharmaceutical, medical device and diagnostic companies through market disruption across Asia, Europe, and North America. Combines deep scientific foundation (PhD Chemistry, drug discovery background) with executive leadership experience at Pfizer, Bayer, Roche, and Fresenius. Proven track record managing large-scale portfolios and navigating complex regulatory transformations, including China specific reforms during 15+ years of in-country operations. Specializes in providing actionable strategic insights and market intelligence on China's biopharmaceutical and med-tech landscape, translating regulatory disruption and evolving market policies into commercial strategy. Known for bridging scientific rigor with business acumen while applying agile and lean methodologies to foster product development excellence and deliver measurable outcomes across the entire value chain from drug discovery through commercialization.
Languages
Education
Technical University Dortmund
Ph.D. in Chemistry · Chemistry · Dortmund, Germany
Technical University Dortmund
Master of Science in Chemistry · Chemistry, Chemical Engineering · Dortmund, Germany
Walram-Gymnasium Menden
German High School Diploma · Menden, Germany
Certifications & licenses
Scrum Alliance® Certified Scrum Master (CSM)
Scrum Alliance®
PMI® Project Management Professional (PMP)
PMI®
ScaledAgile Inc.® Certified Lean Portfolio Management (LPM) SAFe 6.0
ScaledAgile Inc.®
University Of St. Gallen Executive Education Certificate On Strategy Execution & Change Management Program
University Of St. Gallen
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