Shin M.

Co-Founder, Chief Executive Officer & Chief Scientific Officer

Brookline, United States

Experience

Nov 2023 - Present
2 years 2 months

Co-Founder, Chief Executive Officer & Chief Scientific Officer

New Wind Therapeutics

  • Prioritize the social mission of advancing cancer research over maximizing profits
  • Develop novel inhibitors targeting cancer stem cells for the treatment of pancreatic cancer
  • Design and direct preclinical drug development
  • Nurture next-generation scientists
  • Published the book chapter “Therapeutic Approaches Targeting Cancer Stem Cells”
  • Listed as one of the “50 Leading Companies of the Year 2024” by The Silicon Review
May 2022 - Nov 2023
1 year 7 months

Scientist III

Sanofi

  • Play a key role in one of the most productive research teams
  • Engage in the development of BTK inhibitors and novel cGVHD treatments
  • Perform high throughput flow cytometry, BTK occupancy assay, ELISA/MSA and related assays
  • Completed the in-vitro pharmacological package of Sanofi’s BTK inhibitors for human B-cells
  • Opened a new avenue for research on BTK in human eosinophils, mast cells and neutrophils
Nov 2018 - Oct 2021
3 years

Postdoctoral Research Fellow

Brigham and Women’s Hospital/Harvard Medical School

  • Coordinate chemistry and biology research to elucidate the mechanisms of coronary heart disease and create novel drug targets
  • Lead project management and research coordination from conception to completion
  • Employ cutting-edge biological research tactics, including single-cell qPCR, single-cell mRNA sequencing with 10X Genomics Chromium Controller and BD Rhapsody from cell capture to library preparation, and mass cytometry (CyTOF) to analyze real-time impacts of treatments
  • Supervise medical students in laboratory settings, providing mentorship, direction, and training to foster academic skill growth
  • Review articles for peer review journals
Feb 2014 - Sep 2018
4 years 8 months

Postdoctoral Research Fellow

Keio University School of Medicine

  • Coordinate chemistry and biology research to create and analyze novel treatments of complex diseases while mastering modern biological research techniques
  • Lead project management and research coordination from conception to completion, publishing a series of research papers focused on graft-versus-host disease
  • Master and employ biological research tactics, including ELISA, PCR, immunoblotting, and immunostaining; coordinate animal research experiments to analyze treatment impacts
  • Supervise PhD students in laboratory settings, providing mentorship, direction, and training to foster academic skill growth
  • Respond and adapt to varying tasks, high-pressure environments, and time-critical projects; play an integral role in editing and proofreading in English and Japanese

Summary

Strategic and ambitious research scientist/entrepreneur with 15+ years of expertise bridging the boundary between immunology/biology and organic chemistry to coordinate novel research in new drug synthesis and elucidation of disease mechanisms.

Mastery of biology/immunology/chemical biology research techniques, including single-cell mRNA sequencing, mouse experiments, conventional and spectral flow cytometry, mass cytometry, western blotting, ELISA, immunostaining, cell culture and multi-step organic synthesis.

Proven ability to lead research from conception to publication stages while serving as a leader in laboratory settings.

Knowledgeable of laboratory safety and hazardous material handling, with expert analytical problem-solving, communication, mentoring and critical thinking skills.

Languages

Japanese
Native
English
Advanced

Education

Mar 2007 - Mar 2012

The University of Western Australia

Doctor of Philosophy · Bio-Organic Chemistry · Australia

Apr 2003 - Mar 2005

Kyoto University

Master of Engineering · Bio-Organic Chemistry · Japan

Apr 1999 - Mar 2003

Kyoto University

Bachelor of Engineering · Chemistry · Japan

Certifications & licenses

Entrepreneurship Essentials

Harvard Business School

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