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Mustafa (Safa) Karagöz

Postdoctoral Researcher

Mustafa Karagöz
Detmold, Germany

Experience

Jul 2023 - Jul 2025
2 years 1 month
Bethesda, United States

Postdoctoral Researcher

National Institutes of Health (NIH), NHLBI

  • Led peptide inhibitor design against UPF1 using RFdiffusion, ProteinMPNN, and AlphaFold2/3; validated candidates with molecular dynamics simulations
  • Screened over 1 million compounds for ataxia fusion proteins via AutoDock Vina; confirmed top hits using GROMACS MD simulations
  • Developed RNA-seq analysis pipelines for nonsense-mediated decay (NMD) studies including isoform quantification and motif discovery
  • Modeled protein-RNA interactions using AlphaFold3 multimers integrated with BioGRID/STRING databases
  • Established computational workflows for transcriptomics and RNA regulation in iPSC-derived human models
Aug 2019 - May 2023
3 years 10 months
Braunschweig, Germany

PhD Researcher

Technische Universität Braunschweig

  • Investigated Legionella pneumophila virulence factors integrating structural biology and interactomics approaches
  • Utilized AlphaFold and Rosetta for modeling pathogen-host interactions; identified druggable targets for therapeutic intervention
  • Purified effector proteins and validated ligand binding using nanoDSF and surface plasmon resonance (SPR)
  • Applied human lung explants to connect molecular mechanisms with tissue-level responses to infection
  • Integrated AP-MS proteomics data with computational modeling to map host-pathogen interaction networks
Apr 2017 - Jul 2019
2 years 4 months
İstanbul, Turkey

Research Assistant

Türkisch-Deutsche Universität

  • Developed computational models for amyloid formation and disordered protein behavior
  • Designed peptide and protein variants using homology modeling, molecular docking, and high-performance computing
  • Established molecular modeling workflows for protein structure-function analysis
Feb 2016 - May 2016
4 months
Turkey

Project Assistant

TÜBİTAK Marmara Technopark (MARTEK)

  • Performed pharmacological assays and biosensor studies for preclinical drug testing
  • Supported automation-based in vivo and ex vivo drug validation protocols
Jun 2014 - Sep 2014
4 months
Portugal

Research Intern

Instituto Gulbenkian de Ciência (IGC)

  • Conducted pharmacological assays and in vivo studies on therapeutic candidates
  • Contributed to synthetic biology and high-throughput screening pipelines
Jun 2013 - Sep 2013
4 months
İstanbul, Turkey

Research Intern

Bogazici University

  • Performed molecular biology assays for drug testing and validation

Industries Experience

See where this freelancer has spent most of their professional time. Longer bars indicate deeper hands-on experience, while shorter ones reflect targeted or project-based work.

Experienced in Biotechnology (9 years), Pharmaceutical (4.5 years), and Education (2.5 years).

Biotechnology
Pharmaceutical
Education

Business Areas Experience

The graph below provides a cumulative view of the freelancer's experience across multiple business areas, calculated from completed and active engagements. It highlights the areas where the freelancer has most frequently contributed to planning, execution, and delivery of business outcomes.

Experienced in Research and Development (9 years).

Research and Development

Summary

Computational biologist with 8+ years of experience bridging experimental biology and computational innovation. Expertise in protein design, structural bioinformatics, and transcriptomics applied to therapeutic discovery. Successfully led projects from molecular modeling to validation in human model systems. Proven ability to integrate multi-omics data, develop computational pipelines, and translate findings into biological insights for undruggable targets.

Skills

Protein Design

  • Alphafold2/3
  • Rfdiffusion
  • Proteinmpnn
  • Rosetta Suite

Structural Biology

  • Molecular Dynamics
  • Pymol/chimerax
  • Gromacs

Computational Methods

  • Python/r Programming
  • Hpc/cloud Computing
  • Bioinformatics Pipelines
  • Bash Scripting

Transcriptomics

  • Rna-seq Analysis
  • Isoform Quantification
  • Motif Discovery
  • Nmd Studies

Experimental Techniques

  • Protein Purification
  • Nanodsf/spr
  • Mass Spectrometry
  • Mammalian/ipsc Culture

Specialized Knowledge

  • Host-pathogen Interactions
  • Drug Discovery Pipelines
  • Multi-omics Integration
  • Undruggable Targets

Technical Skills

  • Protein Design: Alphafold2/3, Rfdiffusion, Proteinmpnn, Rosetta
  • Structural Analysis: Pymol, Chimerax, Gromacs, Autodock Vina
  • Transcriptomics: Rna-seq, Isoform Quantification, Motif Discovery
  • Programming: Python, R, Bash Scripting
  • Computational: Hpc, Cloud Computing, Bioinformatics Pipelines

Languages

German
Native
Turkish
Native
English
Advanced

Education

Aug 2019 - May 2023

Technische Universität Braunschweig

PhD in Biology, Protein interaction and inhibition of L. pneumophila Mip and immunometabolism · Biology · Braunschweig, Germany

Oct 2015 - Jun 2018

Gebze Technical University

M.Sc. Molecular Biology & Genetics, Molecular characterization and identification of the interaction partner of the peptidyl · Molecular Biology & Genetics · Turkey

Oct 2011 - Jun 2015

Gebze Technical University

B.Sc. Molecular Biology & Genetics · Molecular Biology & Genetics · Turkey

Profile

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Frequently asked questions

Do you have questions? Here you can find further information.

Where is Mustafa based?

Mustafa is based in Detmold, Germany.

What languages does Mustafa speak?

Mustafa speaks the following languages: German (Native), Turkish (Native), English (Advanced).

How many years of experience does Mustafa have?

Mustafa has at least 9 years of experience. During this time, Mustafa has worked in at least 5 different roles and for 6 different companies. The average length of individual experience is 2 years and 6 months. Note that Mustafa may not have shared all experience and actually has more experience.

What roles would Mustafa be best suited for?

Based on recent experience, Mustafa would be well-suited for roles such as: Postdoctoral Researcher, PhD Researcher, Research Assistant.

What is Mustafa's latest experience?

Mustafa's most recent position is Postdoctoral Researcher at National Institutes of Health (NIH), NHLBI.

What companies has Mustafa worked for in recent years?

In recent years, Mustafa has worked for National Institutes of Health (NIH), NHLBI and Technische Universität Braunschweig.

Which industries is Mustafa most experienced in?

Mustafa is most experienced in industries like Biotechnology, Pharmaceutical, and Education.

Which business areas is Mustafa most experienced in?

Mustafa is most experienced in business areas like Research and Development (R&D).

Which industries has Mustafa worked in recently?

Mustafa has recently worked in industries like Biotechnology and Pharmaceutical.

Which business areas has Mustafa worked in recently?

Mustafa has recently worked in business areas like Research and Development (R&D).

What is Mustafa's education?

Mustafa holds a Doctorate in Biology from Technische Universität Braunschweig, a Master in Molecular Biology & Genetics from Gebze Technical University and a Bachelor in Molecular Biology & Genetics from Gebze Technical University.

What is the availability of Mustafa?

Mustafa is immediately available full-time for suitable projects.

What is the rate of Mustafa?

Mustafa's rate depends on the specific project requirements. Please use the Meet button on the profile to schedule a meeting and discuss the details.

How to hire Mustafa?

To hire Mustafa, click the Meet button on the profile to request a meeting and discuss your project needs.

Average rates for similar positions

Rates are based on recent contracts and do not include FRATCH margin.

1000
750
500
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Market avg: 820-980 €
The rates shown represent the typical market range for freelancers in this position based on recent contracts on our platform.
Actual rates may vary depending on seniority level, experience, skill specialization, project complexity, and engagement length.