Douglas N.
Independent Data Analyst – Tech & Life Sciences
Experience
Oct 2024 - Present
1 year 3 monthsGermany
Independent Data Analyst – Tech & Life Sciences
p53-REACT
- Supported partner centers in adopting AI and LLMs-based predictive models for small-molecule discovery and therapeutic response using their genomic databases, designing failure modes for AI, and reducing feature-engineering time by 25%.
- Performed Python analysis and improved domain motion coverage by 30% through integration of free energy data with conformational modeling, mapping heterogeneous protein states for accurate structure–function analysis.
Jul 2023 - Jan 2024
7 monthsUnited States
Scientific Researcher (MSCA Secondment)
Rensselaer Polytechnic Institute (RPI)
- Engineered bacterial expression systems for plant-derived small-molecule biosynthesis of varying size, conformation, and group substitution, validated by HPLC-LC of 120+ compounds.
- Deployed machine learning workflows on AWS SageMaker to generate experimentally testable hypotheses, achieving accurate protein conformational stability predictions and reducing model training time by 15%.
Sep 2022 - Sep 2024
2 years 1 monthGermany
Scientific Researcher (EU Marie Curie Fellow)
Technical University of Munich (TUM)
- Led a project modeling protein conformational transitions in cancer-linked systems (p53 family and inhibitor interactions), achieving improvements in mutant reactivation efficiency.
- Collaborated with 10+ groups to predict binding interfaces and allosteric mutations, aligning computational and experimental results for potential clinical trial design.
Sep 2017 - Aug 2022
5 yearsBrazil
University Lecturer/Visiting Researcher & Visiting Professor
Feira de Santana State University/Federal University of ABC
Jul 2016 - Sep 2017
1 year 3 monthsBrazil
Post-Doctoral Researcher
Federal University of Rio de Janeiro
- Investigated glioblastoma-linked systems from NMR spectroscopy, cryo-EM datasets, and molecular dynamics simulations to gain mechanistic insights across 8 protein targets.
- Designed protein unfolding landscape models and aggregation-propensity maps, generating 20+ molecular biomarkers based on rigorous management of thermodynamic perturbations.
Jul 2015 - Jul 2016
1 year 1 monthFrance
Research Fellow
Institut Pasteur
- Worked with 12 custom nucleases for gene editing using NGS-based off-target prediction models.
- Applied the ARIA computational tool to calculate molecular structures from NMR data, improving editing specificity by 20%.
Summary
PhD in Molecular Biology and Marie Skłodowska-Curie Fellow. Experienced scientific researcher and data specialist with a trajectory in structural biology, biochemistry, and AI-driven biological research. Certified in Python, SQL, and R, with strong skills in interpreting complex datasets, translating research findings into actionable insights, and critically assessing novelty, impact, and methodology.
Languages
Portuguese
NativeEnglish
AdvancedFrench
AdvancedGerman
IntermediateEducation
UNICAMP
BS, Chemical Engineering · Chemical Engineering · Brazil
UNICAMP and University of Montpellier
MSc, Molecular and Functional Biology – Biochemistry · Molecular and Functional Biology – Biochemistry · Montpellier, France
UNICAMP and University of Montpellier
PhD, Molecular and Functional Biology – Biochemistry · Molecular and Functional Biology – Biochemistry · Montpellier, France
Certifications & licenses
Python
R
SQL
Need a freelancer? Find your match in seconds.
Try FRATCH GPT More actions
Similar Freelancers
Discover other experts with similar qualifications and experience
- English
- Deutsch
2025 © FRATCH.IO GmbH. All rights reserved.