Sandeep Kesh - Postdoctoral Researcher

Q: Where is Sandeep based?

Sandeep is based in Jena, Germany and can operate in on-site , hybrid , and remote work models.

Q: What languages does Sandeep speak?

Sandeep speaks the following languages: English (Advanced), German (Intermediate) .

Q: How many years of experience does Sandeep have?

Sandeep has at least 9 years of experience. During this time, Sandeep has worked in at least 6 different roles and for 6 different companies . The average length of individual experience is 1 year and 7 months . Note that Sandeep may not have shared all experience and actually has more experience.

Q: What is Sandeep's latest experience?

Sandeep's most recent position is Postdoctoral Researcher at Friedrich Schiller University .

Q: What companies has Sandeep worked for in recent years?

In recent years, Sandeep has worked for Friedrich Schiller University and University Hospital Jena .

Q: Which industries is Sandeep most experienced in?

Sandeep is most experienced in industries like Pharmaceutical , Biotechnology , and Healthcare . Sandeep also has some experience in Chemical .

Q: Which business areas is Sandeep most experienced in?

Sandeep is most experienced in business areas like Research and Development (R&D) , Product Development , and Quality Assurance (QA) .

Q: Which industries has Sandeep worked in recently?

Sandeep has recently worked in industries like Healthcare , Pharmaceutical , and Biotechnology .

Q: Which business areas has Sandeep worked in recently?

Sandeep has recently worked in business areas like Quality Assurance (QA) , Research and Development (R&D) , and Product Development .

Recommended expert

Jena, Germany

Experience

Apr 2024 - Present

1 year 10 months

Jena, Germany

Postdoctoral Researcher

Friedrich Schiller University

Established and optimized viral detection assays (SARS-CoV-2, IAV) in A549 and Vero cell lines using qPCR, immunofluorescence and AFM-based morphology analysis to generate quantitative data on viral protein expression and particle quality
Characterized protein aggregation and fibril formation using NanoFTIR, fluorescence spectroscopy, Raman and ThT assays, linking biophysical signatures to stability and quality attributes of protein formulations
Applied statistics-based data analysis to evaluate assay robustness and variability, supporting QbD-oriented discussions on method performance and critical analytical parameters
Led method development and data interpretation for analytical workflows, collaborating with cross-functional colleagues and training team members on advanced biophysical instrumentation

Sep 2020 - Mar 2024

3 years 7 months

Jena, Germany

Scientific Assistant (PhD Scholar)

University Hospital Jena

Designed and executed robustness studies for cell-based ion channel assays by systematically varying key parameters (cell density, incubation time, cRNA concentration), defining design space and acceptable operating ranges, resulting in comprehensive SOP documentation and enhanced assay reliability
Led product characterization and screening of small molecules, RNA, and DNA targeting CNG ion channels using HPLC, UV-Vis, fluorescence spectroscopy, and DLS, generating integrated datasets on purity, aggregation, and functional activity that informed critical quality attribute (CQA) evaluations
Developed and optimized analytical protocols for RNA and protein quality and stability by implementing rigorous validation steps, supporting preclinical drug development and ensuring accurate assessment of product-related quality attributes

Jul 2017 - Feb 2020

2 years 8 months

United States

Research Assistant

University of Iowa

Developed, synthesized and optimized nanoparticle-based drug formulations using electrophoretic methods, DLS and SLS to characterize particle size, charge and stability, and subsequently optimized formulations for lyophilization for in vivo mouse studies in cystic fibrosis
Designed and evaluated the stability of ubiquinol/gamma-cyclodextrin formulations using Turbiscan, ROS and MTS assays, flow cytometry and DLS, linking analytical results to formulation performance and product quality

Jul 2016 - Jun 2017

1 year

India

Deputy Manager

Development Alternatives

Managed a microbiology lab in a cGMP manufacturing environment, implementing safety protocols and SOPs for pilot testing of a rapid bacterial detection kit, ensuring compliant documentation and contributing to method validation reports
Performed material characterization (XRD, PSD, ITC) to define key material properties, feeding analytical results into risk assessments and formulation decisions for industrial applications

May 2015 - Aug 2015

4 months

Pune, India

Research Internship

National Chemical Laboratory, Pune

Conducted a multi-spectroscopic investigation integrating IR, UV-Vis, ¹³C NMR and molecular dynamics simulations to quantify interactions between BSA and testosterone (protein-ligand interactions)

Apr 2015 - Apr 2016

1 year 1 month

Rourkela, India

Master Thesis Student

National Institute of Technology, Rourkela

Characterized protein-ligand (Lysozyme and Rhodamine B) interactions using biophysical techniques (UV-Vis, fluorescence, CD, molecular docking) to characterize changes in secondary structures

Summary

Scientist with 6+ years’ experience in analytical development and process characterization for biologics and complex formulations, including robustness studies, product characterization and method validation. Hands-on background with chromatographic and spectroscopic methods (HPLC, UV-Vis, fluorescence, DLS, ITC, AFM) and biological assays (ELISA, Nanoluciferase, cell-based assays). Practical exposure to Quality-by-Design concepts and risk-based thinking, now aiming to contribute as a Product Expert / Analytical Process Manager, driving CQA evaluation and QbD-based analytical strategies in biopharmaceutical projects.

Skills

Molecular Biology
Chromatographic (Hplc)
Protein Purification
Rna/dna Extraction
Qpcr
Spectroscopic Techniques
Uv-vis
Fluorescence
Lc-ms
Electrophoretic Methods (Gel Electrophoresis)
Circular Dichroism
Cross-functional Collaboration
Electrophysiology
Chromatography
Dls
Dsf
Dsc
Itc
Flow Cytometry
Turbiscanner
Fluorescence Microscopy
Critical Quality Attributes (Cqas)
Nanoluciferase
Elisa
Legendplex
Sop
Technical And Scientific Presentation
Cell Culture
Virus Propagation
Python
Molecular Dynamics Simulations
Drug Screening
Statistical Analysis

Languages

English

Advanced

German

Intermediate

Education

Sep 2020 - Mar 2026

University Hospital Jena

PhD in Molecular Medicine · Molecular Medicine · Jena, Germany

Jul 2011 - May 2016

National Institute of Technology, Rourkela

Integrated Master of Science in Chemistry · Chemistry · Rourkela, India · 7.8/10

Certifications & licenses

Certification In Gmp

Gmp Academy

Project Management

Friedrich Schiller University

Profile

Created

December 2025

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Frequently asked questions

Do you have questions? Here you can find further information.

Where is Sandeep based?

Sandeep is based in Jena, Germany and can operate in on-site, hybrid, and remote work models.

What languages does Sandeep speak?

Sandeep speaks the following languages: English (Advanced), German (Intermediate).

How many years of experience does Sandeep have?

Sandeep has at least 9 years of experience. During this time, Sandeep has worked in at least 6 different roles and for 6 different companies. The average length of individual experience is 1 year and 7 months. Note that Sandeep may not have shared all experience and actually has more experience.

What roles would Sandeep be best suited for?

Based on recent experience, Sandeep would be well-suited for roles such as: Postdoctoral Researcher, Scientific Assistant (PhD Scholar), Research Assistant.

What is Sandeep's latest experience?

Sandeep's most recent position is Postdoctoral Researcher at Friedrich Schiller University.

What companies has Sandeep worked for in recent years?

In recent years, Sandeep has worked for Friedrich Schiller University and University Hospital Jena.

Which industries is Sandeep most experienced in?

Sandeep is most experienced in industries like Pharmaceutical, Biotechnology, and Healthcare. Sandeep also has some experience in Chemical.

Which business areas is Sandeep most experienced in?

Sandeep is most experienced in business areas like Research and Development (R&D), Product Development, and Quality Assurance (QA).

Which industries has Sandeep worked in recently?

Sandeep has recently worked in industries like Healthcare, Pharmaceutical, and Biotechnology.

Which business areas has Sandeep worked in recently?

Sandeep has recently worked in business areas like Quality Assurance (QA), Research and Development (R&D), and Product Development.

What is Sandeep's education?

Sandeep holds a Doctorate in Molecular Medicine from University Hospital Jena and a Master in Chemistry from National Institute of Technology, Rourkela.

Does Sandeep have any certificates?

Sandeep has 2 certificates. These include: Certification In Gmp and Project Management.

What is the availability of Sandeep?

Sandeep will be available from February 2026.

What is the rate of Sandeep?

Sandeep's rate depends on the specific project requirements. Please use the Meet button on the profile to schedule a meeting and discuss the details.