Chelly Van Vuuren
Technical Scientist
Experience
Technical Scientist
Abbott Diagnostics
- Contributed to the optimisation and troubleshooting of immunoassay and diagnostic reagent workflows.
- Collaborated with R&D, QC, and manufacturing teams to ensure scientific robustness, product quality, and regulatory compliance.
- Evaluated assay performance, identified root causes for deviation, and implemented scientifically sound corrective actions.
- Reviewed and interpreted experimental data to ensure alignment with manufacturing standards and regulatory requirements.
- Designed and executed laboratory investigations (OOS, OOT, stability failures, reagent issues).
- Supported transfer, optimisation, and validation of biochemical and immunoassay processes.
- Authored technical reports and contributed to documentation for regulatory and quality audits.
- Collaborated across teams to troubleshoot complex biological or biochemical issues affecting production.
PhD Researcher
Centre for Chromosome Biology, NUI Galway
- Project: The Role of UBF in Ribosomal DNA Activity Regulation
- Designed and executed multi-step molecular workflows, including protein expression, purification, SDS-PAGE, western blotting, and in-vitro transcription.
- Developed and optimised complex protocols such as Cas9-mediated DNA isolation, enChIP, and protein-interaction assays.
- Conducted advanced microscopy (live cell, FISH, FRAP) and generated and analysed datasets using tools such as ImageJ, Metamorph, Volocity, SoftWoRx.
- Engineered plasmids, created stable cell lines, and performed high-complexity genetic manipulations.
- Synthesised, interpreted, and communicated complex multivariate data.
Aptamer SELEX Project
NCBES
Fluorescence Photodynamic Studies
Leibniz Institute for Age Research
Multiple FRAP/FLAP and centromere biology projects
Centre for Chromosome Biology, NUI Galway
Industries Experience
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Experienced in Biotechnology (10 years), Education (10 years), and Healthcare (4 years).
Business Areas Experience
The graph below provides a cumulative view of the freelancer's experience across multiple business areas, calculated from completed and active engagements. It highlights the areas where the freelancer has most frequently contributed to planning, execution, and delivery of business outcomes.
Experienced in Research and Development (13 years), Product Development (4 years), and Quality Assurance (4 years).
Summary
Biochemistry and cell-biology specialist with a PhD in molecular biology and industry experience as a Technical Scientist at Abbott Diagnostics. Deep expertise in experimental design, molecular workflows, microscopy, genome manipulation, and troubleshooting complex biological systems.
Bringing sharp analytical thinking, high-precision technical review skills, and a creative, systems-level approach to evaluating and developing next-generation AI tools for life-science workflows.
Skilled in critical analysis of biological reasoning, protocol optimisation, experimental troubleshooting, data interpretation, and designing challenging biological scenarios for AI evaluation.
Skills
- Biological Workflow Evaluation
- Experimental Design & Troubleshooting
- Molecular And Cell Biology
- Genome Engineering & Crispr
- Microscopy (Live-cell, Fish, Frap/flap)
- Scientific Writing & Data Interpretation
- Constructing Synthetic Biological Scenarios For Ai Testing
- Developing High-quality Datasets For Model Training
- Molecular Biology: Cloning, Crispr/cas9, Qpcr, Rna Transcription
- Cell Biology: Mammalian Culture, Transfection, Stable Line Generation
- Microscopy: Live Imaging, Fish, Frap, Flap
- Data Analysis: Imagej, Metamorph, Volocity, Softworx
- General: Microsoft Office, Technical Writing, Troubleshooting Workflows
Languages
Education
NUI Galway, Centre for Chromosome Biology
PhD, Molecular Biology · Molecular Biology · Galway, Ireland
Profile
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