Chelly Van vuuren
Technical Scientist
Experience
Technical Scientist
Abbott Diagnostics
- Contributed to the optimisation and troubleshooting of immunoassay and diagnostic reagent workflows.
- Collaborated with R&D, QC, and manufacturing teams to ensure scientific robustness, product quality, and regulatory compliance.
- Evaluated assay performance, identified root causes for deviation, and implemented scientifically sound corrective actions.
- Reviewed and interpreted experimental data to ensure alignment with manufacturing standards and regulatory requirements.
- Designed and executed laboratory investigations (OOS, OOT, stability failures, reagent issues).
- Supported transfer, optimisation, and validation of biochemical and immunoassay processes.
- Authored technical reports and contributed to documentation for regulatory and quality audits.
- Collaborated across teams to troubleshoot complex biological or biochemical issues affecting production.
PhD Researcher
Centre for Chromosome Biology, NUI Galway
- Project: The Role of UBF in Ribosomal DNA Activity Regulation
- Designed and executed multi-step molecular workflows, including protein expression, purification, SDS-PAGE, western blotting, and in-vitro transcription.
- Developed and optimised complex protocols such as Cas9-mediated DNA isolation, enChIP, and protein-interaction assays.
- Conducted advanced microscopy (live cell, FISH, FRAP) and generated and analysed datasets using tools such as ImageJ, Metamorph, Volocity, SoftWoRx.
- Engineered plasmids, created stable cell lines, and performed high-complexity genetic manipulations.
- Synthesised, interpreted, and communicated complex multivariate data.
Aptamer SELEX Project
NCBES
Fluorescence Photodynamic Studies
Leibniz Institute for Age Research
Multiple FRAP/FLAP and centromere biology projects
Centre for Chromosome Biology, NUI Galway
Summary
Biochemistry and cell-biology specialist with a PhD in molecular biology and industry experience as a Technical Scientist at Abbott Diagnostics. Deep expertise in experimental design, molecular workflows, microscopy, genome manipulation, and troubleshooting complex biological systems.
Bringing sharp analytical thinking, high-precision technical review skills, and a creative, systems-level approach to evaluating and developing next-generation AI tools for life-science workflows.
Skilled in critical analysis of biological reasoning, protocol optimisation, experimental troubleshooting, data interpretation, and designing challenging biological scenarios for AI evaluation.
Skills
- Biological Workflow Evaluation
- Experimental Design & Troubleshooting
- Molecular And Cell Biology
- Genome Engineering & Crispr
- Microscopy (Live-cell, Fish, Frap/flap)
- Scientific Writing & Data Interpretation
- Constructing Synthetic Biological Scenarios For Ai Testing
- Developing High-quality Datasets For Model Training
- Molecular Biology: Cloning, Crispr/cas9, Qpcr, Rna Transcription
- Cell Biology: Mammalian Culture, Transfection, Stable Line Generation
- Microscopy: Live Imaging, Fish, Frap, Flap
- Data Analysis: Imagej, Metamorph, Volocity, Softworx
- General: Microsoft Office, Technical Writing, Troubleshooting Workflows
Languages
Education
NUI Galway, Centre for Chromosome Biology
PhD, Molecular Biology · Molecular Biology · Galway, Ireland
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