Asma R.
Researcher in Evolutionary Biology
Experience
Researcher in Evolutionary Biology
Gulbenkian Institute for Molecular Medicine
The aim of the project was to study the evolutionary development of Escherichia coli strains during colonization of the mouse intestine.
This work provides important insights into how evolutionary processes transform microbial coexistence into ecological divergence.
Experimental evolution of E. coli strains in the mouse gut.
Growth and competition assays assess fitness and coexistence.
Whole-genome sequencing and variant analysis of evolved populations.
Data analysis, visualization, and interpretation of evolutionary dynamics.
Team Member
COST Action Genome Editing to Treat Human Diseases
- Participated as a team member in the COST Action Genome Editing to Treat Human Diseases.
Researcher in Biomedical Science
Chemical and Biological Technology Institute ITQB and Biosystems and Integrative Sciences Institute BiolSI, Faculty of Sciences
Performed a multidisciplinary approach with a wide range of biochemical and biophysical techniques.
Used the innovative, cutting-edge CRISPR-Cas9 technique to create a series of mutants.
Strengthened understanding of genetic variations and their effects on microbial metabolic pathways through hands-on experience with genetic manipulation and microbial growth assays.
Maintained exceptional hygiene and sanitisation standards for microbiology investigation.
Conducted laboratory tests under strict conditions for accurate results.
Developed controls for standardising analysis techniques for accurate results.
Researcher in Biomedical Science
Ricardo Jorge Institute
- Study of the RNA expression of cholesterol transporter protein NPC1L1 using RT-PCR.
Researcher in Biomedical Science
Biosystems and Integrative Sciences Institute BiolSI, Faculty of Sciences of Lisbon, University of Lisbon
Dedicated to the advancement of bioactive molecules and materials aimed at enhancing human health, specifically targeting cholesterol absorption and the expression of transporter proteins.
Evaluated the potential of various extracts and infusions derived from natural sources.
Conducted rigorous laboratory experiments under established standards and protocols.
Conducted research into diverse scientific theories, contributing to industry discourse with scholarly publications.
Developed standardized analysis techniques and established controls to ensure consistency and accuracy of experimental results.
Intern
Center of Chemistry & Biochemistry, University of Lisbon & Faculty of Sciences of Bizerte, University of Carthage
- Studied the effect of Opuntia ficus-indica cladodes on cholesterol absorption, regulation of intracellular cholesterol metabolism, and prevention of Alzheimer disease in vitro.
Intern
Technical Center of Food CTAA
- Compared methods of extracting pigments from algae and characterized their antioxidant activity.
Intern
Higher Institute of Food Industries Tunisia - ESIAT
- Studied the composition and antioxidant activity of prickly pear cactus leaves (cladodes).
Intern
Winery Grombalia
Gained knowledge of the winemaking process.
Performed quality control assays on raw materials and finished products.
Intern
National Institute for Research and Physicochemical Analysis INRAP
Acquired knowledge of spectrophotometric analysis using LC-MS and GC-MS.
Worked under a regulated quality system (ISO22588 and ISO17025).
Intern
Oil Factory North Tunisia
Gained practical knowledge of the olive press process.
Performed quality control assays on raw materials and finished products.
Intern
Tunisian Canned Food TUCAL
Gained practical knowledge of the canned tomato process.
Performed quality control assays on raw materials and final products.
Worked under a regulated quality system (ISO22000).
Summary
Dynamic and dedicated researcher with profound knowledge in pharmaceutical and toxicological biochemistry. Experienced in microbial and mammalian cell biology, with expertise in bioinformatics, pharmacokinetic, pharmacodynamic and genetic manipulation techniques. Proven experience in conducting rigorous laboratory experiments and contributing to scientific publications. Seeking opportunities to utilize my expertise to advance human health.
Skills
- Bioinformatics
- Transcriptomics (Star, Psiclass, Cuffdiff, Deseq2, Minimap2)
- Crispr/cas9
- Genomics (Ngs)
- Enzymology
- Metabolomics
- 2d Electrophoresis
- Western Blotting
- Dna/rna Extraction
- Cell Culture
- Hplc, Lc/ms, Gc-ms
- Protein Expression And Purification
- Fourier-transform Infrared Spectroscopy 'Ftir'
- Pharmacokinetics
- Pharmacodynamics
- Laboratory Management
- Originlab Software
- Rt-pcr
- R And Python Basics
- Genome Editing
- Safety Regulations
- Safety Guidelines
- Testing Protocols
- Infectious Bacteria Handling
- Linux
- Docking
- Iso 22000
- Haccp, Iso9001
- Autodock/chemdraw
Languages
Education
University of Carthage
PhD in Biology, Pharmaceutical and toxicological Biochemistry · Biology · Tunisia
Faculty of sciences of Bizerte, University of Carthage
Master's degree in food safety · Food safety · Bizerte, Tunisia
Higher Institute of Food Industries Tunisia - ESIAT
Engineering degree in food industry · Food industry · Tunisia
Certifications & licenses
Food Safety Certificate ISO22000
Technical Center Of Food CTAA
Basics In Light Microscopy
Bioinformatics Methods For Transcriptomics
Johns Hopkins University
Certificate In Gas Chromatography Coupled To Mass Spectrometry GC-MS
Certificate In Statistical Software SPSS
Executive Diploma In Data Analytics
Exploring Pharmaceutical Frontiers In Drug Discovery, Within-Host Dynamics, And Clinical Trials Global Security Awareness
Genomic Data Science Specialization
Global Data Privacy Awareness
Introduction To Small Molecule Drug Discovery & Development
Population Health: Responsible Data Analysis
Leiden University
Project Management: The Basics For Success
University of California, Irvine
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