Rasangi P. - Research Scientist - Metabolomics

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Chicago, United States

Experience

Feb 2025 - Present

11 months

Chicago, United States

Research Scientist - Metabolomics

The University of Chicago

Extract metabolites from a wide range of samples including cell culture, murine tissues, human biopsy and biofluids and quantify concentration using LC-MS
Analyze metabolomics data using specialized software programs (TraceFinder, Compound Discoverer, Skyline etc.)
Engage in the preparation of grant applications, reports, and scientific research manuscripts
Aid the metabolomics platform director in advancing the technologies and managing day-to-day workflow
Collaborate with academic and community-based organizations to develop new research projects
Mentor graduate students and researchers in sample preparation and instrumentation protocols

Jan 2022 - Present

4 years

New Orleans, United States

Postdoctoral Researcher

LSU Health Sciences Center

Design and execute analytical methodologies for LC-MS/MS for a wide variety of compounds including phospholipids, lipid mediators, and fatty acids
Optimize and validate LC-MS methods for data-dependent acquisition (DDA), including Multiple Reaction Monitoring (MRM), Selected Ion Recording (SIR) and MS/MS scans
Conduct method development for data-independent acquisition (DIA)
Develop and implement novel research protocols for sample preparation mainly based on liquid-liquid extraction (LLE) and solid phase extraction (SPE)
Optimize liquid chromatography (LC) methods, such as Reversed-Phase Liquid Chromatography (RPLC) and Hydrophilic Interaction Liquid Chromatography (HILIC)
Deliver analyzed datasets (figures, text, data tables) to investigators and assist in writing manuscripts, presentations, and grant applications
Oversee general scientific operations of the lab to ensure compliance with university policies, federal, and state regulations
Prepare and oversee the implementation of Standard Operating Procedures (SOPs)
Mentor students and staff involved in research projects and internships to ensure adherence to protocols and guidelines

Aug 2016 - Dec 2021

5 years 5 months

Baton Rouge, United States

Graduate Teaching Assistant

Louisiana State University

Supported professors in implementing rigorous teaching and learning experiences
Mentored undergraduate students in General Chemistry and Organic Chemistry laboratory courses
Guided students on laboratory safety and instructed on proper use of equipment including NMR, DLS, FTIR, and wet chemistry techniques
Followed established course outline to prepare lessons and convey information regarding lab procedures and chemistry principles
Taught CHEM 1212 General Chemistry Laboratory, CHEM 2364 Organic Chemistry Laboratory, and CHEM 4010 Macromolecular Systems I across multiple semesters and sessions

Oct 2013 - Jun 2016

2 years 9 months

Colombo, Sri Lanka

Quality Assurance Executive

Bamber & Bruce (Pvt) Ltd

Ensured compliance with ISO/IEC 17025 regulatory standards and their application
Oversaw laboratory testing to identify non-conformance and ensured tests were conducted in accordance with regulatory standards and internal quality control measures
Prepared and oversaw the implementation of Standard Operating Procedures (SOPs)
Conducted tests and inspections on consumer, agricultural, and food products using GC-MS and AAS
Conducted quality-related training for staff
Collaborated with regulatory agencies to obtain and maintain accreditation
Hosted internal audits, proficiency testing, and inter-laboratory comparison programs and performed internal calibrations

May 2012 - Sep 2013

1 year 5 months

Avissawella, Sri Lanka

Quality Executive

Beam Hela Osu Lanka (Pvt) Ltd

Ensured ISO 9001 Quality Management Systems standards were implemented and adhered to
Coordinated drug regulatory submissions to government authorities
Coordinated drug testing activities with contract laboratories
Presented quality-related reports to senior management

Summary

Analytical Chemistry researcher with 3 years of experience in cutting-edge laboratory techniques and instrumentation.

Demonstrated expertise mainly in LC-MS/MS lipidomics and metabolomics, NMR, AAS, DLS, FTIR, UV-Vis, MALDI MS, and Small Angle Neutron and X-ray Scattering (SANS & SAXS). Hands-on experience with LNP (Lipid Nanoparticle) and polymersome synthesis.

Proven track record in working within ISO-regulated environments, ensuring compliance and precision in all analytical processes. Highly skilled in both independent research and collaborative projects, with a commitment to advancing scientific knowledge and innovation.

Languages

English

Advanced

Sinhalese

Advanced

Education

Aug 2016 - Dec 2021

Department of Chemistry, Louisiana State University

PhD · Chemistry · Baton Rouge, United States

Sep 2007 - Sep 2011

Institute of Chemistry

BS · Chemistry · Sri Jayawardenepura Kotte, Sri Lanka

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Experience

Research Scientist - Metabolomics

The University of Chicago

Postdoctoral Researcher

LSU Health Sciences Center

Graduate Teaching Assistant

Louisiana State University

Quality Assurance Executive

Bamber & Bruce (Pvt) Ltd

Quality Executive

Beam Hela Osu Lanka (Pvt) Ltd

Summary

Languages

Education

Department of Chemistry, Louisiana State University

PhD · Chemistry · Baton Rouge, United States

Institute of Chemistry

BS · Chemistry · Sri Jayawardenepura Kotte, Sri Lanka

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