Rasangi P.
Research Scientist - Metabolomics
Experience
Feb 2025 - Present
10 monthsChicago, United States
Research Scientist - Metabolomics
The University of Chicago
- Extract metabolites from a wide range of samples including cell culture, murine tissues, human biopsy and biofluids and quantify concentration using LC-MS
- Analyze metabolomics data using specialized software programs (TraceFinder, Compound Discoverer, Skyline etc.)
- Engage in the preparation of grant applications, reports, and scientific research manuscripts
- Aid the metabolomics platform director in advancing the technologies and managing day-to-day workflow
- Collaborate with academic and community-based organizations to develop new research projects
- Mentor graduate students and researchers in sample preparation and instrumentation protocols
Jan 2022 - Present
3 years 11 monthsNew Orleans, United States
Postdoctoral Researcher
LSU Health Sciences Center
- Design and execute analytical methodologies for LC-MS/MS for a wide variety of compounds including phospholipids, lipid mediators, and fatty acids
- Optimize and validate LC-MS methods for data-dependent acquisition (DDA), including Multiple Reaction Monitoring (MRM), Selected Ion Recording (SIR) and MS/MS scans
- Conduct method development for data-independent acquisition (DIA)
- Develop and implement novel research protocols for sample preparation mainly based on liquid-liquid extraction (LLE) and solid phase extraction (SPE)
- Optimize liquid chromatography (LC) methods, such as Reversed-Phase Liquid Chromatography (RPLC) and Hydrophilic Interaction Liquid Chromatography (HILIC)
- Deliver analyzed datasets (figures, text, data tables) to investigators and assist in writing manuscripts, presentations, and grant applications
- Oversee general scientific operations of the lab to ensure compliance with university policies, federal, and state regulations
- Prepare and oversee the implementation of Standard Operating Procedures (SOPs)
- Mentor students and staff involved in research projects and internships to ensure adherence to protocols and guidelines
Aug 2016 - Dec 2021
5 years 5 monthsBaton Rouge, United States
Graduate Teaching Assistant
Louisiana State University
- Supported professors in implementing rigorous teaching and learning experiences
- Mentored undergraduate students in General Chemistry and Organic Chemistry laboratory courses
- Guided students on laboratory safety and instructed on proper use of equipment including NMR, DLS, FTIR, and wet chemistry techniques
- Followed established course outline to prepare lessons and convey information regarding lab procedures and chemistry principles
- Taught CHEM 1212 General Chemistry Laboratory, CHEM 2364 Organic Chemistry Laboratory, and CHEM 4010 Macromolecular Systems I across multiple semesters and sessions
Oct 2013 - Jun 2016
2 years 9 monthsColombo, Sri Lanka
Quality Assurance Executive
Bamber & Bruce (Pvt) Ltd
- Ensured compliance with ISO/IEC 17025 regulatory standards and their application
- Oversaw laboratory testing to identify non-conformance and ensured tests were conducted in accordance with regulatory standards and internal quality control measures
- Prepared and oversaw the implementation of Standard Operating Procedures (SOPs)
- Conducted tests and inspections on consumer, agricultural, and food products using GC-MS and AAS
- Conducted quality-related training for staff
- Collaborated with regulatory agencies to obtain and maintain accreditation
- Hosted internal audits, proficiency testing, and inter-laboratory comparison programs and performed internal calibrations
May 2012 - Sep 2013
1 year 5 monthsAvissawella, Sri Lanka
Quality Executive
Beam Hela Osu Lanka (Pvt) Ltd
- Ensured ISO 9001 Quality Management Systems standards were implemented and adhered to
- Coordinated drug regulatory submissions to government authorities
- Coordinated drug testing activities with contract laboratories
- Presented quality-related reports to senior management
Summary
Analytical Chemistry researcher with 3 years of experience in cutting-edge laboratory techniques and instrumentation.
Demonstrated expertise mainly in LC-MS/MS lipidomics and metabolomics, NMR, AAS, DLS, FTIR, UV-Vis, MALDI MS, and Small Angle Neutron and X-ray Scattering (SANS & SAXS). Hands-on experience with LNP (Lipid Nanoparticle) and polymersome synthesis.
Proven track record in working within ISO-regulated environments, ensuring compliance and precision in all analytical processes. Highly skilled in both independent research and collaborative projects, with a commitment to advancing scientific knowledge and innovation.
Languages
English
AdvancedSinhalese
AdvancedEducation
Aug 2016 - Dec 2021
Department of Chemistry, Louisiana State University
PhD · Chemistry · Baton Rouge, United States
Sep 2007 - Sep 2011
Institute of Chemistry
BS · Chemistry · Sri Jayawardenepura Kotte, Sri Lanka
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