Vijendra (A.) K.

Guest Lecturer

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Pune, India

Experience

Mar 2023 - Jul 2025
2 years 5 months
Pune, India

Guest Lecturer

Dept. of Bioinformatics, SPPU

  • Curriculum design, lecture delivery, student assessment, and academic mentorship in metabolic modeling and systems biology.
  • Developed and implemented a graduate-level curriculum in metabolic modelling and systems biology.
  • Delivered comprehensive lectures covering genome-scale modeling, flux balance analysis (FBA), and systems-level strain engineering.
  • Conducted in-depth case studies on applications of systems biology in strain engineering.
  • Facilitated interactive sessions to enhance understanding and application of metabolic modeling techniques.
  • Evaluated student performance through assignments and projects, providing constructive feedback.
  • Enhanced students' knowledge and skills in metabolic modeling and systems biology, providing a solid foundation for careers in biotechnology.
  • Successfully equipped students with advanced techniques such as genome-scale modeling and FBA to increase competence in systems-level strain engineering.
Mar 2022 - Present
3 years 10 months
Pune, India

Principal Project Associate

CSIR-NCL

  • Developed glioblastoma-specific metabolic models to identify potential synthetic lethal gene targets.
  • Participated in SARS-CoV-2 genome sequencing using Nanopore pipelines, focusing on lineage typing and mutational hotspot identification.
  • Applied Flux Balance Analysis (FBA) using the COBRA Toolbox to model Indian lung-specific metabolism and SARS-CoV-2 host interactions.
  • Engineered Pseudomonas fluorescens strains to enhance the bioconversion of ferulic acid to vanillin.
  • Constructed metabolic models with transcriptomic constraints for Penicillin V production in engineered microbes.
  • Utilized bioinformatics tools for sequencing data analysis, data mining, and database management.
  • Identified potential therapeutic targets for glioblastoma, contributing to cancer research.
  • Contributed to understanding SARS-CoV-2 epidemiology by identifying key mutations and lineages.
  • Enhanced efficiency of bioconversion processes, improving production of valuable compounds.
  • Successfully engineered P. fluorescens strains.
Jan 2014 - Feb 2021
7 years 2 months
Mumbai, India

Ph.D. Research Scholar

IIT Bombay

  • Investigated gene regulation and epistasis within melibiose metabolism of Saccharomyces cerevisiae.
  • Utilized mutant strain libraries, transformation techniques, and mating assays to validate regulatory models.
  • Developed ODE-based mathematical models simulating glucose-galactose and melibiose pathway dynamics and genetic switches.
  • Conducted sensitivity analysis to identify parameters influencing metabolic pathways.
  • Performed data analysis and interpretation of experimental results.
  • Documented research findings and assisted in drafting scientific publications.
  • Validated multiple regulatory models and uncovered key regulatory insights into melibiose metabolism.
  • Built and tested ODE-based mathematical models.
  • Elucidated sensitive parameters affecting pathway dynamics, informing genetic engineering strategies.
Jan 2014 - Jun 2016
2 years 6 months
Mumbai, India

Teaching Associate

Dept. of Biosciences & Bioengineering, IIT Bombay

  • Delivered lab sessions and assisted in course design, student mentorship, and assessment.
  • Conducted hands-on laboratory sessions for undergraduate and postgraduate courses in yeast molecular biology.
  • Prepared and delivered practical demonstrations for microbial physiology courses.
  • Assisted in design and execution of synthetic biology experiments.
  • Mentored students in experimental techniques and data analysis.
  • Graded student assignments and provided constructive feedback.
  • Facilitated enhanced student skills and understanding through hands-on lab sessions.
  • Supported effective learning of complex topics in molecular biology, microbial physiology, and synthetic biology.
Nov 2011 - Jan 2014
2 years 3 months
Pune, India

Project Assistant

CSIR-NCL

  • Isolated microbial strains for terpene production in agarwood.
  • Characterized volatile oil profiles and fermentation products.
  • Performed routine laboratory procedures including media preparation and sterilization.
  • Managed inventory of laboratory supplies and equipment.
  • Assisted in data collection and analysis for experiments.
  • Contributed to identification of microbial strains capable of terpene production.
  • Aided in comprehensive characterization of volatile oil profiles.
  • Supported upkeep and maintenance of laboratory infrastructure.
Jun 2010 - Aug 2011
1 year 3 months
Pune, India

M.Sc. Final Project

University of Pune

  • Characterized marine-derived rhamnolipid biosurfactant from Pseudomonas aeruginosa.
  • Assessed antimicrobial properties of rhamnolipid biosurfactant.
  • Evaluated anti-diabetic activities of rhamnolipid biosurfactant.
  • Analyzed surface-active properties of rhamnolipid biosurfactant.
  • Provided comprehensive characterization of rhamnolipid biosurfactant, potentially leading to novel applications.
  • Demonstrated antimicrobial and anti-diabetic properties.
  • Elucidated surface-active behavior of characterized biosurfactant.

Summary

Ph.D. in Biosciences & Bioengineering with research experience in systems biology, genome-scale metabolic modeling, and data-driven biological analysis. Actively developing skills in Python and machine learning to complement expertise in COBRA-based modeling. Eager to contribute to company ’s modeling platform by supporting innovation, ensuring scientific rigor, and learning from cross-functional R&D teams.

Skills

  • Expertise In Developing And Applying Genome-scale Metabolic Models (Gems) Using Cobra Toolbox And Cobrapy For Diverse Systems Including Mammalian And Microbial.

  • Proficient In Integrating Transcriptomic Data With Gems To Enhance Flux Predictions And Model Accuracy.

  • Hands-on Experience In Sars-cov-2 Genome Sequencing Using Nanopore Pipelines, Including Flye, Rna-seq, Medaka, Multiqc, And Pangolin.

  • Skilled In Strain Engineering Of Microorganisms To Enhance Bioconversion And Product Formation.

  • Extensive Knowledge Of Matlab Programming And Python, For Data Analysis, Modeling, And Simulation.

  • Proven Ability To Design And Deliver Graduate-level Courses On Metabolic Modeling And Systems Biology.

  • Experienced In Applying Fba, Fva, Optknock, And Gene Deletion Analysis For Metabolic Flux Optimization And Synthetic Lethality Studies.

  • Strong Foundation In Molecular Biology, Microbial Physiology, And Synthetic Biology Through Teaching And Research Experience.

  • Python

  • Matlab

  • Nextflow

  • Metabolic Modeling

  • Fba

  • Cobrapy

  • Cobra Toolbox

  • Communication

  • Collaboration

  • Problem-solving

  • Adaptability

  • Analytical Thinking

  • Predictive Modeling

  • Genomic Data Analysis

  • Systems Biology

  • R&d Collaboration

  • Process Optimization

  • Statistical Analysis

  • Experimental Biology

  • Yeast Metabolic Engineering

  • Microbial Growth And Physiology

  • Micro-fermentation And Automation

Languages

English
Advanced
Hindi
Advanced
Marathi
Advanced

Education

Oct 2014 - Jun 2021

Indian Institute of Technology Bombay

Ph.D. in Biosciences & Bioengineering · Biosciences & Bioengineering · Mumbai, India

Oct 2009 - Jun 2011

University of Pune

M.Sc. in Microbiology · Microbiology · Pune, India

Oct 2006 - Jun 2009

Modern College of Science, Pune University

B.Sc. in Microbiology · Microbiology · Pune, India

Certifications & licenses

Data Science And Machine Learning (DSML)

MIT Professional Education

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