Vijendra (A.) K.

Guest Lecturer

Pune, India

Experience

Mar 2023 - Jul 2025
2 years 5 months
Pune, India

Guest Lecturer

Savitribai Phule Pune University

  • Curriculum design, lecture delivery, student assessment, and academic mentorship in the field of metabolic modeling and systems biology.
  • Developed and implemented a graduate-level curriculum in metabolic modelling and systems biology.
  • Delivered comprehensive lectures covering genome-scale modeling, flux balance analysis (FBA), and systems-level strain engineering.
  • Conducted in-depth case studies focusing on applications of systems biology in strain engineering.
  • Facilitated interactive sessions to enhance the understanding and application of metabolic modeling techniques.
  • Evaluated student performance through assignments and projects, providing constructive feedback for improvement.
  • Enhanced students' knowledge and skills in metabolic modeling and systems biology, providing a solid foundation for careers in biotechnology and related fields.
  • Successfully equipped students with advanced techniques such as genome-scale modeling and FBA, increasing their competence in systems-level strain engineering.
Mar 2022 - Present
3 years 9 months
Pune, India

Principal Project Associate

CSIR-National Chemical Laboratory

  • Metabolic model development, genome sequencing, data analysis, microbial strain engineering, project management, and scientific reporting.
  • Developed glioblastoma-specific metabolic models to identify potential synthetic lethal gene targets.
  • Participated in SARS-CoV-2 genome sequencing using Nanopore pipelines, focusing on lineage typing and mutational hotspot identification.
  • Applied flux balance analysis (FBA) using the COBRA Toolbox to model Indian lung-specific metabolism and SARS-CoV-2 host interactions.
  • Engineered Pseudomonas fluorescens strains to enhance the bioconversion of ferulic acid to vanillin.
  • Constructed metabolic models incorporating transcriptomic constraints for penicillin V production in engineered microbes.
  • Utilized bioinformatics tools for analysis of sequencing data, data mining, and database management.
  • Identified potential therapeutic targets for glioblastoma through metabolic modeling, contributing to advancements in cancer research.
  • Contributed to the understanding of SARS-CoV-2 epidemiology by identifying key mutations and lineages through genomic sequencing.
  • Enhanced the efficiency of bioconversion processes, leading to improved production of valuable compounds.
  • Successfully engineered P. fluorescens strains.
Jan 2014 - Feb 2021
7 years 2 months
Mumbai, India

Ph.D. Research Scholar

Indian Institute of Technology Bombay

  • Investigated gene regulation and epistasis within the melibiose metabolism of Saccharomyces cerevisiae.
  • Utilized mutant strain libraries, transformation techniques, and mating assays to validate regulatory models.
  • Developed ordinary differential equation (ODE)-based mathematical models simulating glucose-galactose and melibiose pathway dynamics and genetic switches.
  • Conducted sensitivity analysis to identify sensitive parameters influencing metabolic pathways.
  • Performed data analysis and interpretation to draw meaningful conclusions from experimental results.
  • Documented research findings and assisted in drafting scientific publications.
  • Validated multiple regulatory models and uncovered key regulatory insights into melibiose metabolism.
  • Successfully built and tested ODE-based mathematical models.
  • Elucidated sensitive parameters affecting pathway dynamics using sensitivity analysis, informing genetic engineering strategies.
Jan 2014 - Jun 2016
2 years 6 months
Mumbai, India

Teaching Associate

Indian Institute of Technology Bombay

  • Delivered hands-on laboratory sessions for undergraduate and postgraduate courses in yeast molecular biology.
  • Prepared and delivered practical demonstrations for microbial physiology courses.
  • Assisted in the design and execution of synthetic biology experiments.
  • Mentored students in experimental techniques and data analysis.
  • Graded student assignments and provided constructive feedback to enhance learning outcomes.
  • Facilitated enhanced student skills and understanding through hands-on lab sessions.
  • Supported effective learning of complex topics in molecular biology, microbial physiology, and synthetic biology.
Nov 2011 - Jan 2014
2 years 3 months
Pune, India

Project Assistant

CSIR-National Chemical Laboratory

  • Isolated microbial strains for terpene production in agarwood.
  • Characterized volatile oil profiles and fermentation products.
  • Performed routine laboratory procedures, including media preparation and sterilization.
  • Managed inventory of laboratory supplies and equipment.
  • Assisted in data collection and analysis for various experiments.
  • Contributed to the identification of microbial strains capable of terpene production.
  • Aided in comprehensive characterization of volatile oil profiles.
  • Supported the upkeep and maintenance of laboratory infrastructure.
Jun 2010 - Aug 2011
1 year 3 months
Pune, India

M.Sc. Final Project

University of Pune

  • Characterized marine-derived rhamnolipid biosurfactant from Pseudomonas aeruginosa.
  • Assessed antimicrobial properties of rhamnolipid biosurfactant.
  • Evaluated anti-diabetic activities of rhamnolipid biosurfactant.
  • Analyzed surface-active properties of rhamnolipid biosurfactant.
  • Provided a comprehensive characterization of rhamnolipid biosurfactant, potentially leading to novel applications.
  • Demonstrated antimicrobial and anti-diabetic properties.
  • Elucidated the surface-active behavior of characterized biosurfactant.

Summary

Ph.D. in Biosciences & Bioengineering with research experience in systems biology, genome-scale metabolic modeling, and data-driven biological analysis.

Actively developing skills in Python and machine learning to complement expertise in COBRA-based modeling.

Eager to contribute to company’s modeling platform by supporting innovation, ensuring scientific rigor, and learning from cross-functional R&D teams.

Languages

English
Advanced
Hindi
Advanced
Marathi
Advanced

Education

Oct 2014 - Jun 2021

Indian Institute of Technology Bombay

Ph.D. · Biosciences & Bioengineering · Mumbai, India

Oct 2009 - Jun 2011

University of Pune

M.Sc. · Microbiology · Pune, India

Oct 2006 - Jun 2009

Modern College of Science, Pune University

B.Sc. · Microbiology · Pune, India

Certifications & licenses

Data Science And Machine Learning (DSML)

MIT Professional Education

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