Harshita S.

Research Assistant

Glasgow, United Kingdom

Experience

Dec 2024 - Jun 2025
7 months

Research Assistant

Shared Research Facility, University of Glasgow

  • Processed and integrated Visium spatial transcriptomics samples using SCTransform to correct batch effects, following rigorous QC to exclude low-quality spots and failed samples.
  • Annotated cell clusters using Azimuth and known marker genes, visualised spatial distribution over H&E-stained tissue, and delineated tumour vs. non-tumour regions for region-specific analysis.
  • Conducted differential gene expression and pathway enrichment analysis between high and low stress groups to evaluate stress-induced alterations in the tumour microenvironment.
Sep 2024 - Present
1 year 3 months

Graduate Teaching Assistant

University of Glasgow

  • Led one-on-one lab sessions for undergraduate, postgraduate and PhD students for the following courses: Python programming and SQL database, R programming, genomics and sequence analysis, transcriptomics analysis and scRNA analysis.
  • Guided students in constructing bioinformatics pipelines, specifically focused on next-generation sequencing (NGS), transcriptomics, and scRNA analysis.
Apr 2022 - Feb 2023
11 months

Junior Scientific Analyst

Genotypic Technology Pvt Ltd.

  • Developed robust transcriptomics analysis pipelines for gene expression analysis, enhancing pipeline accuracy and efficiency, along with adhering to GCP and ISO 9001:2015 standards.
  • Managed and conducted comprehensive analysis of big datasets and generated reports that included thorough biological interpretations of the results.
  • Spearheaded the maintenance of comprehensive project documentation and planning, ensuring clarity and organisation across all project stages.
  • Efficiently managed assigned tasks, optimising team productivity and ensuring on-time project delivery.
  • Engaged in regular client interactions to understand their requirements, provide updates, and ensure satisfaction with deliverables.
  • Manually annotated cancer variants, both somatic and germline, following ACMG guidelines, enhancing the accuracy and relevance of genetic information for clinical use.
Aug 2021 - Nov 2021
4 months

Bioinformatics Intern

The Gene Box

  • Conducted comprehensive analysis of metagenomic and metatranscriptomic big data to support advanced research initiatives.
  • Conducted data preprocessing using Python, ensuring data quality and readiness for analysis.
  • Manually curated cancer genomic data following ACMG guidelines, enhancing the accuracy and relevance of genetic information for clinical use.

Summary

I am an early-career Bioinformatician with over three years of combined academic and industry experience.

My work has strengthened my interest in applying computational methods to explore genetic mechanisms in human disease, and IATAC-seq and cloud-based workflows, while contributing to impactful research in developmental biology and disease genomics.

Languages

English
Advanced

Education

Sep 2023 - Sep 2024

University of Glasgow

Masters in Bioinformatics · Bioinformatics · Glasgow, United Kingdom · Merit

Jul 2016 - Jul 2021

KIIT School of Biotechnology

Integrated Bachelors and Masters in Biotechnology · Biotechnology · India · Distinction

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