John (Phd) L.
QC Chemist Scientist
Experience
Jul 2025 - Present
6 monthsSan Diego, United States
QC Chemist Scientist
Sapu Bioscience
- Characterize nanoparticle formulated small-molecule drug products via test methods involving HPLC, GC, and Karl Fischer titration according to cGMP regulations.
- Develop and validate HPLC assay and purity test methods which adhere to USP and ICH standards.
Jun 2025 - Present
7 monthsUnited States
Reviewer
Mercor / Handshake
- Review sophomore and graduate-level tasks in chemistry for adherence to rubric criteria.
Jun 2025 - Present
7 monthsUnited States
Tasker
Mercor / Handshake
- Wrote graduate-level tasks to challenge AI model of a high-profile client for image and text-based problems in organic chemistry.
Jun 2024 - May 2025
1 yearSan Diego, United States
Patent Examiner
US Patent and Trademark Office
- Examine patents in the biotechnology and organic chemistry fields.
- Conduct prior art searches, review technical documents, and determine patentability based on adherence to U.S. rules and statutes.
- Draft office actions, communicate with applicants and attorneys, ensure quality customer service and patent examination.
Mar 2022 - Oct 2023
1 year 8 monthsSan Diego, United States
Scientist I
Molecular Assemblies, Inc.
- Independently developed analytical and preparative methods for modified nucleotide tetraphosphates using RP-HPLC and AEX-FPLC.
- Investigated byproduct formation during enzymatic DNA synthesis processes, analyzing oligos and their digested nucleosides by LC-MS.
- Maintained and troubleshot HPLC and LC-MS systems to ensure data quality and instrument uptime.
Summary
PhD chemist with extensive experience in analytical method development and QC for modified oligonucleotides and their precursors. My expertise includes operating and troubleshooting LC-MS and HPLC systems for in-process and final product analysis. I have a strong background in developing and optimizing methods for a variety of analytes using techniques such as RP-HPLC, AEX-FPLC, and LC-MS, directly supporting the characterization of nucleic acid therapeutics. Familiarity with cGMP environments and developing and validating HPLC test methods in accordance to USP and ICH guidelines.
Languages
English
NativeEducation
Sep 2017 - Mar 2022
UC San Diego
PhD · Organic Chemistry · San Diego, United States
Sep 2013 - Jul 2017
UC San Diego
B.S in Chemistry · Chemistry · San Diego, United States
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