MSc Research: Atomistic Study of the Conformational Dynamics of the ADPDK Membrane Protein

Investigating the structural and functional dynamics of the PC1-PC2 (Polycystin) ion channel implicated in ADPKD.

Performing homology modeling and molecular dynamics simulations to explore conformational states and drug-binding behaviour.

Utilizing NAMD and VMD for simulation workflows, with Python scripts for trajectory analysis and property extraction and Markov Model analysis.

Aiming to derive biologically relevant insights into channel function, binding free energy and potential therapeutic targets through atomistic modeling and docking simulations.

Experience handling FASTA data formats, scripted tools to parse, analyze, and visualize results with pandas, Matplotlib, and Plotly.

Developed scalable Java and PLSQL-based modules for a large insurance product platform, optimising claim workflows.

Designed and optimised complex SQL queries, stored procedures, and triggers to support robust application functionality.

Proposed and implemented backend batch automation that improved user experience and system responsiveness, increasing productivity by 20%.

Worked cross-functionally with stakeholders, demonstrating strong communication, collaboration, and delivery ownership.