Responsibilities:
Key Achievements:
Impact:
Main project: Canagliflozin in combination with enzalutamide to improve prostate cancer treatment in a preclinical study.
Skills:
In vitro; cell culturing (biosafety level I & II)
In vivo; mouse xenografts
RNA-seq analysis; bioinformatics; drug discovery and molecular docking
q-RT-PCR; western blot; RNA & protein extraction
Proliferation & clonogenic assays; flow cytometry; Seahorse assay; ELISA; spectrophotometry; IHC; lentiviral shRNA knockdown
Main projects:
Canagliflozin as a promising anti-androgen treatment for prostate cancer
Canagliflozin in combination with radiotherapy to improve prostate cancer and lung cancer treatments
PSMA PET as a radiotherapy response assessment tool in metastatic prostate cancer at Juravinski Cancer Centre
Skills:
In vitro; cell culturing; BLV2; in vivo; mouse xenografts
RNA-seq analysis; bioinformatics; drug discovery and molecular docking
Surface plasmon resonance (SPR); CESTA; q-RT-PCR; western blot; flow cytometry; Seahorse assay; ELISA; spectrophotometry; IHC; lentiviral shRNA knockdown; siRNA knockdown
Main project: The roles of H₂S on hepatic acetyl-CoA and liver lipid metabolism in the Cardiovascular & Metabolism Research Unit (CMRU).
Skills:
In vitro cell culturing; animal model of CSE knockout; IHC; q-RT-PCR; western blot
Biochemical analysis; atomic absorption spectrometry; spectrophotometry; fluorescence spectroscopy
Bioequivalence Center, Faculty of Pharmacy
Skills:
HPLC; gas chromatography; spectrophotometry; in vivo mouse module
I am a scientist with over 7 years of hands-on research and teaching experience in cancer biology, biochemistry, chemistry, drug discovery, metabolism, pharmacology and cardiovascular diseases. Skilled in both in vitro and in vivo preclinical models, molecular biology techniques, and data analysis. I have contributed to multiple published clinical and preclinical studies and collaborated closely with academic and industry teams. I have experience as a freelancer in AI training projects within the biology and chemistry domains.
Discover other experts with similar qualifications and experience
2025 © FRATCH.IO GmbH. All rights reserved.