Characterizing multicellular inflammatory signaling in disease contexts hallmarked by neuroinflammation
Identifying therapeutic targets in T lymphocytes and reactive astrocytes aimed at treating multiple sclerosis
Optimizing isolation and culture of pure glial cells
Developing novel genomic analysis pipelines to study conserved inflammatory responses across disease contexts
Jan 2019 - Dec 2023
5 years
Boston, United States
Research Assistant
Boston Children’s Hospital
Detailed the functional and spatial characteristics of immune cell populations at the borders of the brain during development
Employed and optimized various microscopy approaches to visualize the meninges as an interface between the skull bone marrow and brain
Performed chemical tissue clearing and lightsheet imaging of various tissues to evaluate structural aspects of the brain borders
Built semi-automated imaging and computational pipelines to analyze imaging data and detail cell localization and migration
Analyzed single-cell sequencing data to further cluster and characterize brain border-associated immune cells
Jan 2018 - Dec 2019
2 years
Boston, United States
Undergraduate Research Assistant
Harvard Medical School
Conducted research on endothelial cell dynamics and blood-brain barrier leakage assay optimization
Employed various in-vivo techniques to evaluate tight junction permeability and endothelial cell extravasation
Constructed a semi-automated pipeline for the 3-D reconstruction of the electron microscopy imaging of the neurovascular unit
Developed multiple statistical metrics and analysis pipelines to aid in analyzing imaging data sets
Jan 2017 - Dec 2018
2 years
Boston, United States
Undergraduate Research Assistant
Northeastern University
Explored the relationship between emotional granularity and the self-regulation of mental and physiological responses towards stressful stimuli
Assessed responses to various psychological tests through the acquisition of emotion word networks and various physiological metrics (i.e. perspiration, EEG, impedance)
Performed computational analysis of collected data as it relates to better psychotherapeutic outcomes for PTSD patients
Languages
English
Native
Spanish
Advanced
Education
Oct 2016 - May 2020
Northeastern University
BS · Behavioral Neuroscience · Boston, United States · 3.745